Lectures cover mechanical ventilators and the physiologic effects of mechanical ventilation on acid-base status, cardiopulmonary function and other homeotatic mechanisms in anesthetized animals; high frequency ventilation in relation to other forms of mechanical respiratory support; recently developed anesthetic agents, techniques, and their clinical applications; interactions between nonanesthetic drugs and their effects on surgical patient response to anesthetic and anesthetic-related agents. Prerequisite: Fourth-year standing in veterinarycurriculum or consent of instructor. 1 hour or 1/4 unit.